When students have a broader understanding of the research areas available, it can help them determine which type of research best aligns with their interests and career goals. Many possibilities exist for research opportunities through medical laboratories and research abroad (both are broad categories). In addition to offering various types of learning opportunities, these two types of research provide students with diverse opportunities to develop specific skills.
Basic science research is concerned with the investigation of basic biological mechanisms—the way in which cellular processes work, how diseases arise on a molecular level, the way drugs interact with biological systems, and how variations in an individual’s genes affect their health. Most universities with a strong research focus maintain basic science laboratories dedicated specifically to the areas of biochemistry, molecular biology, microbiology, pharmacology, and pathology.
When working as a student in this area, you may be involved with clinical trials that evaluate new medications, observational studies that assess the effectiveness of an intervention, historical (retrospective) reviews of a patient’s health record, and multicenter studies that follow a large group of patients over time (prospective). As you participate in these activities, you will gain the skills needed to develop clinically significant research questions and answer them with the application of the scientific method.
Although the above-mentioned activities are valuable in developing your ability to research patient care, they are most importantly valuable in bridging the gap between the academic and clinical environments.
Research into public health investigates disease patterns, causes, treatments, and solutions on a large scale or “population level.” For example, a student might explore how infectious diseases spread, determine what factors put individuals at risk for developing such diseases, evaluate how well current efforts to vaccinate individuals against these diseases are working, study obstacles to accessing health services, or look at social and environmental conditions that affect people’s ability to live healthily. Various methods of collecting and using empirical data will be used to conduct this type of research, including statistical techniques, survey methods, and population-based model frameworks.
For any student who is interested in a career in community health, public health, or international health, conducting these types of projects is a very valuable educational opportunity. Today’s healthcare professionals are increasingly seeing that the knowledge they gain from conducting research into larger populations helps to inform their practice of preventive medicine and ultimately benefits all their patients.
Translational research connects the basic scientific discoveries of the laboratory with the application of that knowledge to the clinical setting; it is often described as the “bench-to-bedside” continuum of research. In other words, translational research applies what we know in the lab to problems we see in our patients every day. An increasing number of medical laboratories and international research partnerships over the last decade have developed opportunities for physician-investigators to engage in this type of research.
Examples of translational research include using animal models to evaluate laboratory-discovered therapies, developing molecular diagnostic tools, constructing ways to deliver medications, and making personalized genomic applications. Like many other areas of medicine and science, conducting translational research involves collaboration among basic scientists, clinical researchers, engineers, and others.
Research is not just about having clinical expertise; it also requires specific skills in the area of research. These include the ability to perform statistical analyses, conduct literature searches, write scientifically, present data effectively, carry out laboratory procedures, and think critically.
Most universities teach research methodology, provide training in biostatistics, and offer workshops in scientific writing. You should take full advantage of these resources while you are still in medical school and begin to learn how to use reference management software and understand the principles of research ethics and the methods of literature review so that you can easily become involved in research.
The skill that you will develop through your training will be to ask the right questions. The main element in research is curiosity. Curiosity leads to questions about phenomena that are not completely understood.
Develop a habit of asking questions about everything you see and do, and just because “everyone does it this way,” be sure to find out what evidence supports that method.